Invention Grant
- Patent Title: Altered peptide ligands of GAD65
- Patent Title (中): 改变GAD65的肽配体
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Application No.: US12295793Application Date: 2007-03-30
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Publication No.: US07994279B2Publication Date: 2011-08-09
- Inventor: Anthony Quinn
- Applicant: Anthony Quinn
- Applicant Address: US OH Toledo
- Assignee: The University of Toledo
- Current Assignee: The University of Toledo
- Current Assignee Address: US OH Toledo
- Agency: MacMillan, Sobanski & Todd, LLC
- International Application: PCT/US2007/008980 WO 20070330
- International Announcement: WO2007/114959 WO 20071011
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/04 ; C07K5/00 ; C07K17/00
Abstract:
Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
Public/Granted literature
- US20090305340A1 ALTERED PEPTIDE LIGANDS OF GAD65 Public/Granted day:2009-12-10
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