Invention Grant
- Patent Title: Cytokine design
- Patent Title (中): 细胞因子设计
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Application No.: US10581856Application Date: 2004-12-06
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Publication No.: US07994281B2Publication Date: 2011-08-09
- Inventor: Vicente R. Tur , Albert Martinus Van der Sloot , Margaret M. Mullally , Robbert H. Cool , Eva E. Szegezdi , Afshin Samali , Gregorio Fernandez-Ballester , Luis Serrano , Wilhelmus J. Quax
- Applicant: Vicente R. Tur , Albert Martinus Van der Sloot , Margaret M. Mullally , Robbert H. Cool , Eva E. Szegezdi , Afshin Samali , Gregorio Fernandez-Ballester , Luis Serrano , Wilhelmus J. Quax
- Applicant Address: DE Heidelberg IE Galway NL Groningen
- Assignee: European Molecular Biology Laboratory,National University of Ireland,University of Groningen
- Current Assignee: European Molecular Biology Laboratory,National University of Ireland,University of Groningen
- Current Assignee Address: DE Heidelberg IE Galway NL Groningen
- Agency: Woodcock Washburn LLP
- Priority: GB0328261.3 20031205
- International Application: PCT/IB2004/004335 WO 20041206
- International Announcement: WO2005/056596 WO 20050623
- Main IPC: C07K14/52
- IPC: C07K14/52 ; C07K14/525
Abstract:
The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.
Public/Granted literature
- US20080044376A1 Cytokine Design Public/Granted day:2008-02-21
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