Invention Grant
US07994327B2 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds
有权
4-氨基-2-（2,6-二氧代哌啶-3-基）异二氢吲哚-1,3-二酮化合物的制备方法
- Patent Title: Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds
- Patent Title (中): 4-氨基-2-（2,6-二氧代哌啶-3-基）异二氢吲哚-1,3-二酮化合物的制备方法
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Application No.: US11479823Application Date: 2006-06-29
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Publication No.: US07994327B2Publication Date: 2011-08-09
- Inventor: Chuansheng Ge , George W. Muller , Roger Chen , Manohar Tukaram Saindane
- Applicant: Chuansheng Ge , George W. Muller , Roger Chen , Manohar Tukaram Saindane
- Applicant Address: US NJ Summit
- Assignee: Celgene Corporation
- Current Assignee: Celgene Corporation
- Current Assignee Address: US NJ Summit
- Agency: Jones Day
- Main IPC: C07D401/04
- IPC: C07D401/04
Abstract:
The present invention provides new processes for the preparation of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds which are useful, for example, for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. The invention can provide improved and/or efficient processes for the commercial production of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds, including, but not limited to, unsubstituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione.
Public/Granted literature
- US20070004920A1 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds Public/Granted day:2007-01-04
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