A defect is detected on a storage medium of a disk drive. A location of the defect is determined, within a smallest addressable unit of data stored on the storage medium. An indication of the location is stored in a memory. A location of a sensor of the disk drive relative to the data stored on the storage medium is monitored. A response of at least one of a defect detector of the disk drive, a read channel controller of the disk drive, and a servo controller of the disk drive is changed based on the location of the sensor relative to the data stored on the storage medium and the stored indication of the location of the defect.