An opto-electric hybrid module capable of reducing the propagation loss of light beams, and a manufacturing method thereof. An opto-electric hybrid module in which a light-emitting element and a light-receiving element are mounted on the front surface side of an electric circuit board E, and an optical waveguide W1 is bonded to the back surface side thereof. The optical waveguide W1 includes a core having opposite end portions formed as light reflection portions. Portions of the core near the opposite end portions are formed as extensions extending from the light reflection portions toward the light-emitting element and the light-receiving element. The extensions and are positioned in through holes for light propagation formed in the electric circuit board E, and have distal end surfaces and in face-to-face relationship with a light-emitting portion of the light-emitting element and a light-receiving portion of the light-receiving element, respectively.