Automated clock relationship detection may quickly and reliably detect a clock relationship with minimal latency while reducing problems due to metastability occurring at a solitary instant or extended over multiple clock periods. Automated clock relationship detection between two clocks may comprise (a) a shift register synchronizer that reduces the possibility of metastability while capturing and temporarily storing samples of the first clock in response to cycles of the second clock and (b) an evaluator that processes the samples to determine the relationship. A clock relationship detector may also determine the relationship of two clocks by arbitrating a plurality of preliminary determinations of the relationship. Delays may be applied so that each of several detectors receives a clock at a different time, which may avoid metastability in the majority of detectors. The relationship may be used to reliably determine an operating mode of logic driven by one of the clocks.