Invention Grant
- Patent Title: Biomarkers for peripheral artery disease
- Patent Title (中): 外周动脉疾病的生物标志物
-
Application No.: US11597667Application Date: 2005-05-26
-
Publication No.: US08008020B2Publication Date: 2011-08-30
- Inventor: Eric T. Fung , John P. Cooke , Xiao-Ying Meng , Tai-Tung Yip , Fujun Zhang
- Applicant: Eric T. Fung , John P. Cooke , Xiao-Ying Meng , Tai-Tung Yip , Fujun Zhang
- Applicant Address: US TX Austin US CA Palo Alto
- Assignee: Vermillion, Inc.,Board of Trustees of the Leland Stanford Junior University
- Current Assignee: Vermillion, Inc.,Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US TX Austin US CA Palo Alto
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Peter F. Corless; Melissa Hunter-Ensor, Esq.
- International Application: PCT/US2005/018728 WO 20050526
- International Announcement: WO2005/121758 WO 20051222
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
This invention provides biomarkers whose concentrations in blood plasma are associated with the presence or absence of PAD in the patient from whom the plasma sample is taken. The invention also provides biomarkers for distinguishing between PAD patients who are long claudicators and PAD patients who are not. In addition, the invention provides methods for identifying additional biomarkers, methods for detecting the biomarkers in patients, and methods for identifying agents, including pharmaceutical agents, which interact with the biomarkers and are useful for preventing or treating PAD in patients.
Public/Granted literature
- US20080081342A1 Biomarkers for peripheral artery disease Public/Granted day:2008-04-03
Information query
IPC分类:
