Invention Grant
US08008023B2 Natural ligand of G protein coupled receptor RCC356 and uses thereof
有权
G蛋白偶联受体RCC356的天然配体及其用途
- Patent Title: Natural ligand of G protein coupled receptor RCC356 and uses thereof
- Patent Title (中): G蛋白偶联受体RCC356的天然配体及其用途
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Application No.: US12152275Application Date: 2008-05-12
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Publication No.: US08008023B2Publication Date: 2011-08-30
- Inventor: Frédéric Sallman , Alex Veithen , Magali Philippeau
- Applicant: Frédéric Sallman , Alex Veithen , Magali Philippeau
- Applicant Address: BE Brussels
- Assignee: Chemcom S.A.
- Current Assignee: Chemcom S.A.
- Current Assignee Address: BE Brussels
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Kathleen Williams; Amy DeCloux
- Priority: EP05447046 20050303
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K14/00
Abstract:
The invention relates to the identification of isovaleric acid as a natural ligand of the RCC356 G-protein coupled receptor (GPCR). The invention encompasses the use of the interaction of RCC356 polypeptides and isovaleric acid as the basis of screening assays for agents that modulate the activity of the RCC356 receptor. The invention also encompasses diagnostic and other assays performed based upon the RCC356/isovaleric acid interaction, as well as kits for performing diagnostic and screening assays.
Public/Granted literature
- US20090264526A1 Natural ligand of G protein coupled receptor RCC356 and uses thereof Public/Granted day:2009-10-22
Information query
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