Invention Grant
US08008027B2 Methods of screening for compounds that modulate the activity of ADEC, a chemokine expressed in inflamed adenoid
失效
筛选调节ADEC活性的化合物的方法，ADEC在发炎腺样体中表达的趋化因子
- Patent Title: Methods of screening for compounds that modulate the activity of ADEC, a chemokine expressed in inflamed adenoid
- Patent Title (中): 筛选调节ADEC活性的化合物的方法，ADEC在发炎腺样体中表达的趋化因子
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Application No.: US12730953Application Date: 2010-03-24
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Publication No.: US08008027B2Publication Date: 2011-08-30
- Inventor: Karl J. Guegler , Phillip R. Hawkins , Craig G. Wilde , Jeffrey J. Seilhamer
- Applicant: Karl J. Guegler , Phillip R. Hawkins , Craig G. Wilde , Jeffrey J. Seilhamer
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Foley & Lardner LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/567
Abstract:
The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.
Public/Granted literature
- US20100279333A1 METHODS OF TREATMENT WITH ANTIBODIES TO A CHEMOKINE EXPRESSED IN INFLAMED ADENOID Public/Granted day:2010-11-04
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