Invention Grant
- Patent Title: Competitive receptor binding assay for detecting beta-glucans
- Patent Title (中): 用于检测β-葡聚糖的竞争性受体结合测定
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Application No.: US11959550Application Date: 2007-12-19
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Publication No.: US08008031B2Publication Date: 2011-08-30
- Inventor: Mei-Li Wu , Hso-Chi Chaung , Tzou-Chi Huang , Wen-Bin Chung , Hui-Ju Hung
- Applicant: Mei-Li Wu , Hso-Chi Chaung , Tzou-Chi Huang , Wen-Bin Chung , Hui-Ju Hung
- Applicant Address: TW
- Assignee: National Pingtung University of Science and Technology
- Current Assignee: National Pingtung University of Science and Technology
- Current Assignee Address: TW
- Agency: Husch Blackwell LLP
- Agent Robert C. Haldiman
- Main IPC: G01N33/567
- IPC: G01N33/567 ; G01N33/566 ; G01N33/549 ; G01N33/00
Abstract:
The present invention provides a method for detecting a beta-glucan having immunomodulatory activity in a human cell, which uses a test cell line that stably expresses human dectin-1 molecule on the cell surface and does not express other glucan receptors and a specific amount of a marker beta-glucan that specifically binds to human dectin-1 molecule for detection.
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