Invention Grant
- Patent Title: Method utilizing enzyme substrates producing insoluble fluorescent products and chromogens, and use in combination with enzyme substrates producing soluble products
- Patent Title (中): 利用产生不溶性荧光产物和色原体的酶底物的方法,并与产生可溶性产物的酶底物组合使用
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Application No.: US11725088Application Date: 2007-03-16
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Publication No.: US08008059B1Publication Date: 2011-08-30
- Inventor: Geoffrey N. Roth , Jonathan N. Roth
- Applicant: Geoffrey N. Roth , Jonathan N. Roth
- Applicant Address: US IN Goshen
- Assignee: Micrology Laboratories, LLC
- Current Assignee: Micrology Laboratories, LLC
- Current Assignee Address: US IN Goshen
- Agency: Botkin & Hall, LLP
- Main IPC: C12N1/00
- IPC: C12N1/00 ; C12N1/20 ; C12N1/10 ; C12N1/12 ; C12N1/16 ; C12Q1/04 ; C12Q1/02 ; C12N9/14 ; C12N9/52 ; C12N9/60

Abstract:
A method of detection of cells, microorganisms, or molecules by the use of various combinations of fluorogens and a chromogens which yield fluorophores and chromophores when cleaved by specific enzymes and which can be viewed by UV and visible light. Included is the method of application of a family of compounds producing both insoluble fluorophores and chromophores identified as dual enzyme substrates.
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