Invention Grant
- Patent Title: Anti-inflammatory A-aminocyclolactam compounds
- Patent Title (中): 抗炎A-氨基环内酰胺化合物
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Application No.: US11573851Application Date: 2005-08-10
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Publication No.: US08008288B2Publication Date: 2011-08-30
- Inventor: David J. Grainger , David John Fox
- Applicant: David J. Grainger , David John Fox
- Applicant Address: GB Cambridge
- Assignee: Cambridge Enterprise Limited
- Current Assignee: Cambridge Enterprise Limited
- Current Assignee Address: GB Cambridge
- Agency: VLP Law Group LLP
- Agent Richard G. A. Bone
- Priority: GB0418375.2 20040818
- International Application: PCT/GB2005/003139 WO 20050810
- International Announcement: WO2006/018609 WO 20060223
- Main IPC: C07D453/06
- IPC: C07D453/06 ; C07D487/08 ; A61K31/439 ; A61K31/55

Abstract:
The invention provides compounds, compositions, and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, for the preparation of a medicament intended to treat an inflammatory disorder wherein y is any integer from 1 to 8; z is any integer from 1 to 8; with the proviso that y and z cannot both equal 1; X is —C —(Y)k—(R1)n or SO2—(Y)k—(R1)n; k is 0 or 1; Y is a cycloalkyl or polycyloalkyl group (such as an adamantyl, adamantanemethyl, bicyclooctyl, cyclohexyl, cyclopropyl group); or Y is a cycloalkenyl or polycycloalkenyl group.
Public/Granted literature
- US20080076755A1 Anti-Inflammatory Agents Public/Granted day:2008-03-27
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