Invention Grant
- Patent Title: Tyrosine kinase inhibitors
- Patent Title (中): 酪氨酸激酶抑制剂
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Application No.: US12605690Application Date: 2009-10-26
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Publication No.: US08008295B2Publication Date: 2011-08-30
- Inventor: Christopher J. Dinsmore , Douglas C. Beshore , Jeffrey M. Bergman , Craig W. Lindsley
- Applicant: Christopher J. Dinsmore , Douglas C. Beshore , Jeffrey M. Bergman , Craig W. Lindsley
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Li Su; David A. Muthard
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/445 ; A61K31/40 ; A61K31/4523
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises an indole-sulfonamide moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Public/Granted literature
- US20100041652A1 TYROSINE KINASE INHIBITORS Public/Granted day:2010-02-18
Information query
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