Invention Grant
- Patent Title: Histamine H3 receptor agents, preparation and therapeutic uses
- Patent Title (中): 组胺H3受体剂，制剂及治疗用途
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Application No.: US11917941Application Date: 2006-06-28
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Publication No.: US08008296B2Publication Date: 2011-08-30
- Inventor: Lisa Selsam Beavers , Don Richard Finley , Robert Alan Gadski , Philip Arthur Hipskind , William Joseph Hornback , Cynthia Darshini Jesudason , Richard Todd Pickard , Takako Takakuwa , Grant Mathews Vaught
- Applicant: Lisa Selsam Beavers , Don Richard Finley , Robert Alan Gadski , Philip Arthur Hipskind , William Joseph Hornback , Cynthia Darshini Jesudason , Richard Todd Pickard , Takako Takakuwa , Grant Mathews Vaught
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Dan L. Wood
- International Application: PCT/US2006/025328 WO 20060628
- International Announcement: WO2007/005503 WO 20070111
- Main IPC: A61K31/535
- IPC: A61K31/535 ; A61K31/497 ; A61K31/445 ; C07D413/00 ; C07D409/00 ; C07D207/00
Abstract:
The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases. (Formula I).
Public/Granted literature
- US20100160319A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES Public/Granted day:2010-06-24
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