Invention Grant
- Patent Title: Compounds for the inhibition of histone deacetylase
- Patent Title (中): 用于抑制组蛋白脱乙酰酶的化合物
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Application No.: US11855416Application Date: 2007-09-14
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Publication No.: US08008344B2Publication Date: 2011-08-30
- Inventor: Chung-Yang Huang , Chia-Nan Chen , Wei-Jan Huang , Chih-Hsiang Huang , Li-Ling Chi , Chiou-Ping You
- Applicant: Chung-Yang Huang , Chia-Nan Chen , Wei-Jan Huang , Chih-Hsiang Huang , Li-Ling Chi , Chiou-Ping You
- Applicant Address: TW Taipei
- Assignee: Naturewise Biotech and Medicals Corporation
- Current Assignee: Naturewise Biotech and Medicals Corporation
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C.
- Agent Anthony King
- Main IPC: A61K31/352
- IPC: A61K31/352 ; C07D311/32
Abstract:
The invention relates to a compound represented by the following formula (I): and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an agent for enhancing the neurite outgrowth and preventing or treating of diseases associated with HDAC in particular, tumor or cell proliferative diseases. In particular, the compounds of the invention can be used as an agent for anti-neurodegenerative diseases and human spinal muscular atrophy (SMA).
Public/Granted literature
- US20090076130A1 COMPOUNDS FOR THE INHIBITION OF HISTONE DEACETYLASE Public/Granted day:2009-03-19
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