Invention Grant
- Patent Title: Polymer stabilized neuropeptides
- Patent Title (中): 聚合物稳定的神经肽
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Application No.: US10647561Application Date: 2003-08-25
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Publication No.: US08008435B2Publication Date: 2011-08-30
- Inventor: Michael David Bentley , Michael James Roberts
- Applicant: Michael David Bentley , Michael James Roberts
- Applicant Address: US CA San Francisco
- Assignee: Nektar Therapeutics
- Current Assignee: Nektar Therapeutics
- Current Assignee Address: US CA San Francisco
- Agent Susan T. Evans
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
A substantially hydrophilic conjugate is provided having a peptide that is capable of passing the blood-brain barrier covalently linked to a water-soluble nonpeptidic polymer such as polyethylene glycol. The conjugate exhibits improved solubility and in vivo stability and is capable of passing the blood-brain barrier of an animal.
Public/Granted literature
- US20040038899A1 Polymer stabilized neuropeptides Public/Granted day:2004-02-26
Information query
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