Invention Grant
- Patent Title: Cancer-associated genes
- Patent Title (中): 癌症相关基因
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Application No.: US12099513Application Date: 2008-04-08
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Publication No.: US08008437B2Publication Date: 2011-08-30
- Inventor: Osamu Ohara , Takahiro Nagase , Daisuke Nakajima , Shin-ichi Funahashi
- Applicant: Osamu Ohara , Takahiro Nagase , Daisuke Nakajima , Shin-ichi Funahashi
- Applicant Address: JP Kisarazu-shi JP Tokyo
- Assignee: Kazusa DNA Research Institute Foundation,Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Kazusa DNA Research Institute Foundation,Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Kisarazu-shi JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP.
- Priority: JP2000-389742 20001222
- Main IPC: C07K5/00
- IPC: C07K5/00
Abstract:
The present invention is related to a DNA comprising a nucleotide sequence encoding a polypeptide represented by SEQ ID NO:1 or SEQ ID NO:2. The DNA according to the present invention is highly expressed in prostatic adenocarcinoma and ovarian carcinoma, and is a cancer-associated gene, so that it is possible to inhibit cancer by blocking the binding of the present protein to its ligand. Accordingly, the present antibody is used not only in the detection of the present protein, but also as an agent for the treatment or prevention of cancers such as prostatic adenocarcinoma and ovarian carcinoma.
Public/Granted literature
- US20080262202A1 NOVEL CANCER-ASSOCIATED GENES Public/Granted day:2008-10-23
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