Invention Grant
- Patent Title: Auto-antibodies against the melanocortin-4 receptor
- Patent Title (中): 针对黑皮质素-4受体的自身抗体
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Application No.: US12347153Application Date: 2008-12-31
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Publication No.: US08008446B2Publication Date: 2011-08-30
- Inventor: Karl Hofbauer , Jean-Christophe Peter
- Applicant: Karl Hofbauer , Jean-Christophe Peter
- Applicant Address: CH
- Assignee: University of Basel
- Current Assignee: University of Basel
- Current Assignee Address: CH
- Agency: Pequignot + Myers LLC
- Agent Joyce von Natzmer
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08
Abstract:
Disclosed are biological markers for obesity and methods for diagnosing and treating obesity and related conditions by detecting and modulating the activity of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor. Also disclosed are methods for discovering new therapeutics which modulate the activity of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor, in particular which prevent the binding of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor.
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