Invention Grant
- Patent Title: Nucleic acids encoding chimera botulinum toxin type E
- Patent Title (中): 编码E型嵌合体肉毒毒素的核酸
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Application No.: US12684745Application Date: 2010-01-08
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Publication No.: US08008465B2Publication Date: 2011-08-30
- Inventor: Ester Fernandez-Salas , Lance E. Steward , Todd Herrington , K. Roger Aoki
- Applicant: Ester Fernandez-Salas , Lance E. Steward , Todd Herrington , K. Roger Aoki
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Kenton Abel; Debra Condino
- Main IPC: C12N15/31
- IPC: C12N15/31
Abstract:
The present invention relates to a toxin comprising a modified light chain of a botulinum toxin type E, wherein the modified light chain comprises amino acid sequence PFVNKQFN (SEQ ID NO: 120) at the N-terminus, and amino acid sequence xExxxLL (SEQ ID NO: 112) at the C-terminus, wherein x is any amino acid.
Public/Granted literature
- US20100121042A1 CHIMERA BOTULINUM TOXIN TYPE E Public/Granted day:2010-05-13
Information query
IPC分类:
