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US08008480B2 Process for the purification of meloxicam 有权
美洛昔康净化方法

Process for the purification of meloxicam
Abstract:
A process for purifying meloxicam form I from a crude meloxicam, which comprises: i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt; ii. isolating the meloxicam salt; iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; and iv. adding an acid to the salt solution to precipitate free meloxicam.
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