Invention Grant
- Patent Title: Process for the purification of meloxicam
- Patent Title (中): 美洛昔康净化方法
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Application No.: US12396044Application Date: 2009-03-02
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Publication No.: US08008480B2Publication Date: 2011-08-30
- Inventor: Liam McElroy , Lillian Cromie , Mark Garret
- Applicant: Liam McElroy , Lillian Cromie , Mark Garret
- Applicant Address: IE Newry
- Assignee: Norbrook Laboratories Ltd
- Current Assignee: Norbrook Laboratories Ltd
- Current Assignee Address: IE Newry
- Agency: Cooley LLP
- Priority: GB0623113.8 20061120
- Main IPC: C07D279/16
- IPC: C07D279/16

Abstract:
A process for purifying meloxicam form I from a crude meloxicam, which comprises: i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt; ii. isolating the meloxicam salt; iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; and iv. adding an acid to the salt solution to precipitate free meloxicam.
Public/Granted literature
- US20090163707A1 Process for the Purification of Meloxicam Public/Granted day:2009-06-25
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