An apparatus and method for avoiding interference in a broadband wireless communication system using FCS are provided. The apparatus and method include a receiver for monitoring channel statuses of neighbor cells using signals received from the neighbor cells, an active set generator for generating an active set according to at least one of the channel statuses of the neighbor cells, loads of the neighbor cells, and a performance gain from the neighbor cells, and a BS selector for selecting a serving cell from the active set according to the channel statuses of cells included in the active set. Accordingly, interference is reduced and reception performance is improved.