Invention Grant
US08009889B2 Feature intensity reconstruction of biological probe array 有权
生物探针阵列特征强度重建

  • Patent Title: Feature intensity reconstruction of biological probe array
  • Patent Title (中): 生物探针阵列特征强度重建
  • Application No.: US11769600
    Application Date: 2007-06-27
  • Publication No.: US08009889B2
    Publication Date: 2011-08-30
  • Inventor: Earl A. Hubbell
  • Applicant: Earl A. Hubbell
  • Applicant Address: US CA Santa Clara
  • Assignee: Affymetrix, Inc.
  • Current Assignee: Affymetrix, Inc.
  • Current Assignee Address: US CA Santa Clara
  • Agent Sandra E. Wells
  • Main IPC: G06K9/00
  • IPC: G06K9/00 G01N33/50
Feature intensity reconstruction of biological probe array
Abstract:
The invention provides methods and systems for reconstructing feature intensities from pixel level data. In certain embodiments, the invention uses an empirically determined transfer function to construct a theoretical estimate of pixel level data and then iteratively updates feature intensities based on a minimum multiplicative error between the pixel level data and the theoretical estimate of the pixel level data.
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