Invention Grant
- Patent Title: Detection of proteins from circulating neoplastic cells
- Patent Title (中): 检测来自循环肿瘤细胞的蛋白质
-
Application No.: US12297420Application Date: 2007-04-18
-
Publication No.: US08012480B2Publication Date: 2011-09-06
- Inventor: Robert M. Lorence
- Applicant: Robert M. Lorence
- Applicant Address: US MD Gaithersburg
- Assignee: Wellstat Biologics Corporation
- Current Assignee: Wellstat Biologics Corporation
- Current Assignee Address: US MD Gaithersburg
- Agent Lewis J. Kreisler
- International Application: PCT/US2007/066857 WO 20070418
- International Announcement: WO2007/121465 WO 20071025
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P35/00 ; G01N33/532 ; G01N33/574
Abstract:
The protein EGFR, ERCC1, RRM1, thymidylate synthase, or beta-tubulin from cancer cells is detected in a blood sample by enriching the cancer cells from the blood sample followed by performing on the enriched cancer cells an immunoassay capable of detecting the proteins mentioned above. Cancer patients overexpressing EGFR are treated with an anti-EGFR agent, for example cetuximab, panitumumab, erlotinib or gefitinib.
Public/Granted literature
- US20090098138A1 DETECTION OF PROTEINS FROM CIRCULATING NEOPLASTIC CELLS Public/Granted day:2009-04-16
Information query
IPC分类:
