Invention Grant
US08012683B2 Variants in complement regulatory genes predict age-related macular degeneration
有权
补体调节基因的变体预测年龄相关性黄斑变性
- Patent Title: Variants in complement regulatory genes predict age-related macular degeneration
- Patent Title (中): 补体调节基因的变体预测年龄相关性黄斑变性
-
Application No.: US11706074Application Date: 2007-02-13
-
Publication No.: US08012683B2Publication Date: 2011-09-06
- Inventor: Rando L. Allikmets , Gregory S. Hageman , Michael C. Dean , Albert M. Gold
- Applicant: Rando L. Allikmets , Gregory S. Hageman , Michael C. Dean , Albert M. Gold
- Applicant Address: US IA Iowa City US NY New York US DC Washington
- Assignee: University of Iowa Research Foundation,The Trustees of Columbia University in the City of New York,United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: University of Iowa Research Foundation,The Trustees of Columbia University in the City of New York,United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US IA Iowa City US NY New York US DC Washington
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
Public/Granted literature
- US20080261211A1 Variants in complement regulatory genes predict age-related macular degeneration Public/Granted day:2008-10-23
Information query
