Invention Grant
US08012712B2 Cell-free system for synthesis of proteins derived from cultured mammalian cells
有权
用于合成来自培养的哺乳动物细胞的蛋白质的无细胞系统
- Patent Title: Cell-free system for synthesis of proteins derived from cultured mammalian cells
- Patent Title (中): 用于合成来自培养的哺乳动物细胞的蛋白质的无细胞系统
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Application No.: US11798759Application Date: 2007-05-16
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Publication No.: US08012712B2Publication Date: 2011-09-06
- Inventor: Hiroaki Imataka , Satoshi Mikami , Shigeyuki Yokoyama
- Applicant: Hiroaki Imataka , Satoshi Mikami , Shigeyuki Yokoyama
- Applicant Address: JP Saitama
- Assignee: Riken
- Current Assignee: Riken
- Current Assignee Address: JP Saitama
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2004-333250 20041117
- Main IPC: C12P21/00
- IPC: C12P21/00
Abstract:
Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein synthesis system comprising an extract prepared from cultured mammalian cells and a template mRNA. These factors are one or more selected from the group consisting of eukaryotic translation initiation factors 4E (eIF4E), 2 (eIF2) and 2B (eIF2B), and eukaryotic translational regulator p97.
Public/Granted literature
- US20070281337A1 Cell-free system for synthesis of proteins derived from cultured mammalian cells Public/Granted day:2007-12-06
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