Invention Grant
- Patent Title: Synthetic peptides and methods for treating cancer invasion and metastasis
- Patent Title (中): 合成肽和治疗癌症侵袭和转移的方法
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Application No.: US10350258Application Date: 2003-01-23
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Publication No.: US08012935B2Publication Date: 2011-09-06
- Inventor: Shrirang Netke , Aleksandra Niedzwiecki , Matthias Rath
- Applicant: Shrirang Netke , Aleksandra Niedzwiecki , Matthias Rath
- Applicant Address: US CA Aptos
- Assignee: Matthias W. Rath
- Current Assignee: Matthias W. Rath
- Current Assignee Address: US CA Aptos
- Agency: Geeta Kadambi Riddhi IP LLC
- Main IPC: A61K38/10
- IPC: A61K38/10
Abstract:
The present invention relates to synthetic oligopeptides that exhibit inhibitory activity towards cancer invasion and metastasis. The peptides of the invention comprise PRKPKWDK (SEQ ID:2) peptide corresponding to amino acids of 85 to 92 of the matrix metalloproteinase (MMP-2), and fragments, analogs and homologs. The invention also relates to the uses of such peptides as inhibitory of human cancer invasion and metastasis and further to their therapeutic use in preventing and treating other pathological conditions related to the degradation of extracellular matrix by MMPs.
Public/Granted literature
- US20030139345A1 Synthetic peptides and methods for treating cancer invasion and metastasis Public/Granted day:2003-07-24
Information query
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