Invention Grant
US08012955B2 N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
有权
N-取代 - 杂环烷氧基苯甲酰胺化合物及其使用方法
- Patent Title: N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
- Patent Title (中): N-取代 - 杂环烷氧基苯甲酰胺化合物及其使用方法
-
Application No.: US11963742Application Date: 2007-12-21
-
Publication No.: US08012955B2Publication Date: 2011-09-06
- Inventor: Rajinder Singh , Jiaxin Yu , Hui Hong , Sambaiah Thota , Xiang Xu , Ihab S. Darwish
- Applicant: Rajinder Singh , Jiaxin Yu , Hui Hong , Sambaiah Thota , Xiang Xu , Ihab S. Darwish
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Agent Travis Young
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A01N43/40 ; A01N43/36 ; A61K31/5365 ; A61K31/5383 ; A61K31/55 ; A61K31/445 ; A61K31/40 ; C07D223/00 ; C07D211/40 ; C07D211/54 ; C07D211/00 ; C07D207/00 ; C07D207/06 ; C07D295/02 ; C07D205/00
Abstract:
The present invention provides N-substituted-heterocycloalkyloxybenzamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment of the invention is a compound having the structure in which R1, R2, R3, R4, T, n, w and x are as described herein. In certain embodiments of the invention, a compound of the present invention activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
Public/Granted literature
- US20090186894A1 N-Substituted-Heterocycloalkyloxybenzamide Compounds and Methods of Use Public/Granted day:2009-07-23
Information query
IPC分类:
