Invention Grant
US08012965B2 Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
有权
桥联的双环芳基和桥连的双环杂芳基取代的三唑可用作axl抑制剂
- Patent Title: Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
- Patent Title (中): 桥联的双环芳基和桥连的双环杂芳基取代的三唑可用作axl抑制剂
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Application No.: US11966942Application Date: 2007-12-28
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Publication No.: US08012965B2Publication Date: 2011-09-06
- Inventor: Dane Goff , Jing Zhang , Rajinder Singh , Sacha Holland , Jiaxin Yu , Pingyu Ding , Joane Litvak
- Applicant: Dane Goff , Jing Zhang , Rajinder Singh , Sacha Holland , Jiaxin Yu , Pingyu Ding , Joane Litvak
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Seed IP Law Group PLLC
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/496 ; A61K31/4375 ; A61K31/435 ; A61K31/519 ; A61K31/517 ; A61P9/00 ; A61P17/06 ; A61P35/00 ; A61P27/02 ; A61P19/00 ; C07D403/14 ; C07D495/04 ; C07D471/18

Abstract:
Bridged bicyclic aryl or heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
Public/Granted literature
- US20080176847A1 BRIDGED BICYCLIC ARYL AND BRIDGED BICYCLIC HETEROARYL SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS Public/Granted day:2008-07-24
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