Invention Grant
- Patent Title: Therapeutic agent for chronic obstructive pulmonary disease
- Patent Title (中): 慢性阻塞性肺疾病治疗剂
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Application No.: US11919135Application Date: 2006-04-28
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Publication No.: US08012971B2Publication Date: 2011-09-06
- Inventor: Toshinari Sugasawa , Takashi Nakajima , Hitoshi Fujita , Toshio Kanai
- Applicant: Toshinari Sugasawa , Takashi Nakajima , Hitoshi Fujita , Toshio Kanai
- Applicant Address: JP Osaka-Shi, Osaka
- Assignee: Dainippon Sumitomo Pharma Co., Ltd.
- Current Assignee: Dainippon Sumitomo Pharma Co., Ltd.
- Current Assignee Address: JP Osaka-Shi, Osaka
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2005-132871 20050428; JP2005-154008 20050526
- International Application: PCT/JP2006/309028 WO 20060428
- International Announcement: WO2006/118268 WO 20061109
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K31/5377 ; C07D417/10 ; C07D277/38

Abstract:
Disclosed is a method for the prevention and/or treatment of a chronic obstructive pulmonary disease by administrating a 5-membered cyclic compound represented by the formula below: or a pharmaceutically acceptable salt of the compound or a prodrug of the compound or salt: wherein X represents an oxygen or sulfur atom; R1 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; R2 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; Y1 represents single bond, a substituted or unsubstituted alkylene or the like; the wavy line means an (E) or (Z) coordination; R3 represents a hydrogen atom, a substituted or unsubstituted aryl or the like; Y2 represents a substituted or unsubstituted alkylene or an alkenylene; R4 represents a hydrogen atom, a substituted or unsubstituted alkanoyl or the like; and R5 represents a hydrogen atom or a substituted or unsubstituted alkyl.
Public/Granted literature
- US20090131439A1 Therapeutic agent for chronic obstructive pulmonary disease Public/Granted day:2009-05-21
Information query
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