Invention Grant
- Patent Title: Substituted pyrazinone melanin concentrating hormone receptor-1 antagonists and methods
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Application No.: US12881234Application Date: 2010-09-14
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Publication No.: US08012984B2Publication Date: 2011-09-06
- Inventor: Philip D. Stein , Sharon N. Bisaha , Saleem Ahmad , Khehyong Ngu , William N. Washburn
- Applicant: Philip D. Stein , Sharon N. Bisaha , Saleem Ahmad , Khehyong Ngu , William N. Washburn
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent John Levis; Maureen Gibbons; Jing G. Sun
- Main IPC: A61K31/4965
- IPC: A61K31/4965

Abstract:
The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I wherein R1, R2, R3, R8, and R9 are defined herein. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I.
Public/Granted literature
- US20110003759A1 NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS Public/Granted day:2011-01-06
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