Invention Grant
- Patent Title: Modulators of CFTR
- Patent Title (中): CFTR调制器
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Application No.: US12782967Application Date: 2010-05-19
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Publication No.: US08012999B2Publication Date: 2011-09-06
- Inventor: Sara S. Hadida Ruah , Peter D. J. Grootenhuis , Jinglan Zhou , Brian Richard Bear , Mark T. Miller , Jason McCartney
- Applicant: Sara S. Hadida Ruah , Peter D. J. Grootenhuis , Jinglan Zhou , Brian Richard Bear , Mark T. Miller , Jason McCartney
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: A61K31/443
- IPC: A61K31/443 ; A61K31/4418
Abstract:
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20100227888A1 MODULATORS OF CFTR Public/Granted day:2010-09-09
Information query
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