Invention Grant
US08013140B2 Promoter for introducing a gene into a lymphocyte or blood cell and application thereof
有权
将基因导入淋巴细胞或血细胞的启动子及其应用
- Patent Title: Promoter for introducing a gene into a lymphocyte or blood cell and application thereof
- Patent Title (中): 将基因导入淋巴细胞或血细胞的启动子及其应用
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Application No.: US12195665Application Date: 2008-08-21
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Publication No.: US08013140B2Publication Date: 2011-09-06
- Inventor: Masaya Takemoto , Yasuko Mori , Koichi Yamanishi , Isao Fuke , Yasuyuki Gomi , Michiaki Takahashi
- Applicant: Masaya Takemoto , Yasuko Mori , Koichi Yamanishi , Isao Fuke , Yasuyuki Gomi , Michiaki Takahashi
- Applicant Address: JP Osaka
- Assignee: The Resarch Foundation for Microbial Diseases of Osaka Universtiy
- Current Assignee: The Resarch Foundation for Microbial Diseases of Osaka Universtiy
- Current Assignee Address: JP Osaka
- Agency: King & Spalding LLP
- Agent Susan J. Myers Fitch; Peter J. Dehlinger
- Priority: JP2005-261366 20050908
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; C12N15/85 ; C12P21/00
Abstract:
It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.
Public/Granted literature
- US20090214579A1 PROMOTER FOR INTRODUCING A GENE INTO A LYMPHOCYTE OR BLOOD CELL AND APPLICATION THEREOF Public/Granted day:2009-08-27
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