Invention Grant
US08013157B2 Synthesis of unsaturated piperidines from piperidones with a silyl reagent
有权
用甲硅烷基试剂从哌啶酮合成不饱和哌啶
- Patent Title: Synthesis of unsaturated piperidines from piperidones with a silyl reagent
- Patent Title (中): 用甲硅烷基试剂从哌啶酮合成不饱和哌啶
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Application No.: US12517846Application Date: 2007-12-19
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Publication No.: US08013157B2Publication Date: 2011-09-06
- Inventor: Neelakandha S. Mani , Christie Morrill
- Applicant: Neelakandha S. Mani , Christie Morrill
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Michael J. Atkins
- International Application: PCT/US2007/025991 WO 20071219
- International Announcement: WO2008/079255 WO 20080703
- Main IPC: C07F7/02
- IPC: C07F7/02
Abstract:
Syntheses of unsaturated piperidines from piperidones through a silyl piperidine reagent via the Shapiro reaction and palladium-catalyzed cross-coupling reactions with organo halides.
Public/Granted literature
- US20100324292A1 SYNTHESIS OF UNSATURATED PIPERIDINES FROM PIPERIDONES WITH A SILYL REAGENT Public/Granted day:2010-12-23
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