Invention Grant
- Patent Title: Preparation of rivastigmine and its salts
- Patent Title (中): 制备利凡斯的明及其盐
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Application No.: US12100591Application Date: 2008-04-10
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Publication No.: US08013181B2Publication Date: 2011-09-06
- Inventor: Venkata Naga Brahmeswara Rao Mandava , Venkata Reddy Vajrala , Ganesh Varanasi , Vijay Kumar Adla , Mukund Reddy Jambula , Vijaypal Reddy Kanumathi Reddy
- Applicant: Venkata Naga Brahmeswara Rao Mandava , Venkata Reddy Vajrala , Ganesh Varanasi , Vijay Kumar Adla , Mukund Reddy Jambula , Vijaypal Reddy Kanumathi Reddy
- Applicant Address: IN Hyderabad US NJ Bridgewater
- Assignee: Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.
- Current Assignee: Dr. Reddy's Laboratories Limited,Dr. Reddy's Laboratories, Inc.
- Current Assignee Address: IN Hyderabad US NJ Bridgewater
- Agent Thomas C. McKenzie; Balaram Gupta; Robert A. Franks
- Priority: IN758/CHE/2007 20070410
- Main IPC: C07C269/00
- IPC: C07C269/00
Abstract:
There are provided processes for making rivastigmine. In one embodiment, the process includes reacting S-(−)-[1-(3-hydroxyphenyl)ethyl]dimethylamine with N-ethyl-N-methyl carbamoyl chloride in the presence of an organic base to obtain a free base of rivastigmine.
Public/Granted literature
- US20080255383A1 PREPARATION OF RIVASTIGMINE AND ITS SALTS Public/Granted day:2008-10-16
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