Invention Grant
- Patent Title: Alpha ketoamide compounds as cysteine protease inhibitors
- Patent Title (中): α-酮酰胺化合物作为半胱氨酸蛋白酶抑制剂
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Application No.: US12711217Application Date: 2010-02-23
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Publication No.: US08013183B2Publication Date: 2011-09-06
- Inventor: Michael Graupe , John O. Link , Michael G. Roepel
- Applicant: Michael Graupe , John O. Link , Michael G. Roepel
- Applicant Address: US CA Menlo Park
- Assignee: ViroBay, Inc.
- Current Assignee: ViroBay, Inc.
- Current Assignee Address: US CA Menlo Park
- Agency: Kilpatrick, Townsend & Stockton LLP
- Main IPC: C07C317/48
- IPC: C07C317/48 ; C07D213/34

Abstract:
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
Public/Granted literature
- US20100305331A1 ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS Public/Granted day:2010-12-02
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