Disclosed embodiments of the invention provide automated global optimization methods and systems of OCR, tailored to each document being digitized. A document-specific database is created from an OCR scan of a document of interest, which contains an exhaustive listing of words in the document. Images of each word, taken from all the fonts encountered, are entered into the database and mapped to a corresponding textual representation. After entry of a first instance of an image of a word written in a particular font, each new occurrence of the word in that font can be quickly recognized by image processing techniques. The disclosed methods and systems may be used in conjunction with adaptive character recognition training and word recognition training of the OCR engines.