Aspects of a method and system for amplitude calibration for polar modulation with discontinuous phase may include amplifying a signal via a plurality of amplifiers such that a combined gain of the plurality of amplifiers comprises a coarse amplitude gain, an amplitude offset gain and a calibration gain. A gain of one or more of the plurality of amplifiers may be adjusted to set the coarse amplitude gain, and a gain of one or more remaining ones of the plurality of amplifiers may be adjusted to set the amplitude offset gain and the calibration gain. The setting of the coarse amplitude gain, the calibration gain and/or said amplitude offset gain may be adjusted dynamically and/or adaptively.