Invention Grant
- Patent Title: Antisense modulation of PTP1B expression
- Patent Title (中): PTP1B表达的反义调制
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Application No.: US12046421Application Date: 2008-03-11
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Publication No.: US08017760B2Publication Date: 2011-09-13
- Inventor: Sanjay Bhanot , Lex M. Cowsert , Jacqueline R. Wyatt , Brett P. Monia , Madeline M. Butler , Robert McKay , Susan M. Freier , Kenneth W. Dobie
- Applicant: Sanjay Bhanot , Lex M. Cowsert , Jacqueline R. Wyatt , Brett P. Monia , Madeline M. Butler , Robert McKay , Susan M. Freier , Kenneth W. Dobie
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Jones Day
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K31/70
Abstract:
Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
Public/Granted literature
- US20090124009A1 ANTISENSE MODULATION OF PTP1B EXPRESSION Public/Granted day:2009-05-14
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