An exhaust after-treatment system for a vehicle including a dosing agent that is selectively injected into an exhaust from a dosing agent supply includes a first module that determines a level of a dosing agent source and a second module that determines whether the vehicle is at a convenient location for replenishing the dosing agent source. A third module selectively inhibits vehicle operation if the level of the dosing agent source is below a threshold level and the vehicle is at the convenient location.