Invention Grant
US08025803B2 Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma
失效
使用色谱底物降低衍生自血浆的溶液中ADAMTS13的量
- Patent Title: Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma
- Patent Title (中): 使用色谱底物降低衍生自血浆的溶液中ADAMTS13的量
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Application No.: US12667751Application Date: 2008-07-07
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Publication No.: US08025803B2Publication Date: 2011-09-27
- Inventor: Francoise Bridey , Roland Schmitthaeusler
- Applicant: Francoise Bridey , Roland Schmitthaeusler
- Applicant Address: FR Les Ulis
- Assignee: LFB Biotechnologies
- Current Assignee: LFB Biotechnologies
- Current Assignee Address: FR Les Ulis
- Agency: Young & Thompson
- Priority: FR0756303 20070705
- International Application: PCT/FR2008/051251 WO 20080707
- International Announcement: WO2009/007661 WO 20090115
- Main IPC: B01D15/08
- IPC: B01D15/08
Abstract:
An ion-exchange chromatography support for reducing the ADAMTS13 amount present in a plasma-derived solution containing human von Willebrand factor. The support includes a large-pore, vinyl polymer-type resin bearing DEAE groups, and a buffer including trisodium citrate, sodium chloride, calcium chloride, glycine and lysine.
Public/Granted literature
- US20100193440A1 USE OF A CHROMATOGRAPHY SUBSTRATE FOR REDUCING THE AMOUNT OF ADAMTS13 IN A SOLUTION DERIVED FROM PLASMA Public/Granted day:2010-08-05
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