Invention Grant
US08025891B2 Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
有权
Porin B（PorB）作为预防和治疗衣原体感染的治疗靶点
- Patent Title: Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
- Patent Title (中): Porin B（PorB）作为预防和治疗衣原体感染的治疗靶点
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Application No.: US12687063Application Date: 2010-01-13
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Publication No.: US08025891B2Publication Date: 2011-09-27
- Inventor: Richard S. Stephens , Diane Kawa
- Applicant: Richard S. Stephens , Diane Kawa
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis
- Agent Carol L Francis; Shweta Chandra
- Main IPC: A61K39/118
- IPC: A61K39/118 ; A61K39/02 ; A61K39/116 ; A61K39/00 ; A61K38/00 ; C07K1/00
Abstract:
The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In specific embodiments the invention features a composition comprising one or more PorB peptides (other than a full-length PorB polypeptide), which peptides contain at least one epitope that can elicit Chlamydia-neutralizing antibodies. The invention also features methods for induction of a protective immune response against infection by Chlamydia and Chlamydophila.
Public/Granted literature
- US20100189738A1 PORIN B (PorB) AS A THERAPEUTIC TARGET FOR PREVENTION AND TREATMENT OF INFECTION BY CHLAMYDIA Public/Granted day:2010-07-29
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