Invention Grant
- Patent Title: Transition metal catalyzed synthesis of N-aminoindoles
- Patent Title (中): 过渡金属催化N-氨基吲哚的合成
-
Application No.: US12576339Application Date: 2009-10-09
-
Publication No.: US08026375B2Publication Date: 2011-09-27
- Inventor: Nis Halland , Marc Nazare , Andreas Lindenschmidt , Omar Rkyek , Matthias Urmann , Jorge Alonso
- Applicant: Nis Halland , Marc Nazare , Andreas Lindenschmidt , Omar Rkyek , Matthias Urmann , Jorge Alonso
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent James W. Bolcsak
- Priority: EP07007585 20070413
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D209/04
Abstract:
The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R0; R1; R2; R3; R4; R5; R6; A1; A2; A3; A4, Q, T and J have the meanings indicated in the claims. The present invention provides a direct transition metal catalyzed process to a wide variety of multifunctional N-aminoindole or N-amino-azaindoles of the formula I from 2-halo-phenylacetylenes or (2-sulfonato)phenyl-acetylenes and N,N-disubstituted hydrazines, useful for the production of pharmaceuticals, diagnostic agents, liquid crystals, polymers, herbicides, fungicidals, nematicidals, parasiticides, insecticides, acaricides and arthropodicides.
Public/Granted literature
- US20100168429A1 Transition metal catalyzed synthesis of N-aminoindoles Public/Granted day:2010-07-01
Information query
