Invention Grant
- Patent Title: HN epitope recognized by avian immune system and antigenic variant newcastle disease viruses carrying changes in the epitope
- Patent Title (中): HN表位被禽类免疫系统和抗原变体新城疫病毒携带表位变化所识别
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Application No.: US11995278Application Date: 2006-03-23
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Publication No.: US08029801B2Publication Date: 2011-10-04
- Inventor: Sun-Hee Cho , Hyuk-Joon Kwon , Young-Jin Ahn , Sun-Joong Kim , Young-Ho Park , Chae-Hyun Kim , Tae-Hwan Kim , Tae-Eun Kim
- Applicant: Sun-Hee Cho , Hyuk-Joon Kwon , Young-Jin Ahn , Sun-Joong Kim , Young-Ho Park , Chae-Hyun Kim , Tae-Hwan Kim , Tae-Eun Kim
- Applicant Address: KR Dugok-Ri, Sinam-Myeon, Chungcheongnam-Do Yesan-Gun KR Suwonsi
- Assignee: KBNP, Inc.,Biopoa, Inc.
- Current Assignee: KBNP, Inc.,Biopoa, Inc.
- Current Assignee Address: KR Dugok-Ri, Sinam-Myeon, Chungcheongnam-Do Yesan-Gun KR Suwonsi
- Agency: Lexyoume IP Group, PLLC
- International Application: PCT/KR2006/001068 WO 20060323
- International Announcement: WO2007/108568 WO 20070927
- Main IPC: A61K39/17
- IPC: A61K39/17 ; C07K7/06 ; C12N7/00

Abstract:
The present invention relates to an epitope of HN protein in Newcastle disease virus which can be recognized by an avian immune system and an antibody against the epitope, a method for detecting a Newcastle disease virus by using the antibody, and an antigenic variant of Newcastle disease virus carrying changes in the epitope. The epitope of HN protein and the antigenic variant of Newcastle disease virus can be used for developing efficient vaccines, and further, in diagnosing the Newcastle disease virus rapidly and exactly.
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