Invention Grant
- Patent Title: Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
- Patent Title (中): 使用热休克蛋白来改善非疫苗治疗方式的治疗效果
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Application No.: US12418724Application Date: 2009-04-06
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Publication No.: US08029808B2Publication Date: 2011-10-04
- Inventor: Pramod K. Srivastava
- Applicant: Pramod K. Srivastava
- Applicant Address: US CT Farmington
- Assignee: University of Connecticut
- Current Assignee: University of Connecticut
- Current Assignee Address: US CT Farmington
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K31/4188
Abstract:
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality.
Public/Granted literature
- US20090208524A1 USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY Public/Granted day:2009-08-20
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