Invention Grant
- Patent Title: Genetic markers for prognosis of antifolate treatment efficacy
- Patent Title (中): 用于预防抗叶酸治疗功效的遗传标记
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Application No.: US12184184Application Date: 2008-07-31
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Publication No.: US08029998B2Publication Date: 2011-10-04
- Inventor: Hendrik Jan Guchelaar , Tom Willem Johannes Huizinga
- Applicant: Hendrik Jan Guchelaar , Tom Willem Johannes Huizinga
- Applicant Address: NL Leiden
- Assignee: Academisch Ziekenhuis Leiden H.O.D.N. LUMC
- Current Assignee: Academisch Ziekenhuis Leiden H.O.D.N. LUMC
- Current Assignee Address: NL Leiden
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
Methods and kits for predicting the efficacy of antifolate (e.g., methotrexate) treatment of rheumatoid arthritis by detecting polymorphisms, particularly single nucleotide polymorphisms, in adenosine pathway genes.
Public/Granted literature
- US20090029379A1 GENETIC MARKERS FOR PROGNOSIS OF ANTIFOLATE TREATMENT EFFICACY Public/Granted day:2009-01-29
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