Invention Grant
- Patent Title: Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
- Patent Title (中): 识别特异性激活人T2R受体的苦配体和相关测定法，用于鉴定人类苦味调节剂
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Application No.: US11555617Application Date: 2006-11-01
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Publication No.: US08030008B2Publication Date: 2011-10-04
- Inventor: Xiaodong Li , Hong Xu , Qing Li , Huixian Tang , Alexey Pronin
- Applicant: Xiaodong Li , Hong Xu , Qing Li , Huixian Tang , Alexey Pronin
- Applicant Address: US CA San Diego
- Assignee: Senomyx, Inc.
- Current Assignee: Senomyx, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Hunton & Williams LLP
- Main IPC: G01N33/567
- IPC: G01N33/567 ; C07K14/705
Abstract:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. The invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by these bitter ligands and related compounds and which may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste.
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Information query
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