Invention Grant
US08030043B2 β-galactoside-α2,3-sialyltransferase, a gene encoding thereof, and a method for producing thereof
失效
β-半乳糖苷-α2,3-唾液酸转移酶及其制备方法
- Patent Title: β-galactoside-α2,3-sialyltransferase, a gene encoding thereof, and a method for producing thereof
- Patent Title (中): β-半乳糖苷-α2,3-唾液酸转移酶及其制备方法
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Application No.: US11918328Application Date: 2006-03-31
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Publication No.: US08030043B2Publication Date: 2011-10-04
- Inventor: Takeshi Yamamoto , Hiroshi Tsukamoto , Yoshimitsu Takakura
- Applicant: Takeshi Yamamoto , Hiroshi Tsukamoto , Yoshimitsu Takakura
- Applicant Address: JP Tokyo
- Assignee: Japan Tobacco Inc.
- Current Assignee: Japan Tobacco Inc.
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: WOPCT/JP2005/007340 20050415; WOPCT/JP2005/010814 20050613
- International Application: PCT/JP2006/306896 WO 20060331
- International Announcement: WO2006/112253 WO 20061026
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12N9/00 ; C12N15/00 ; C12N1/20 ; C12P21/06 ; C12P19/34 ; C12P19/44 ; C07H21/04
Abstract:
The present invention provides a novel β-galactoside-α2,3-sialyltransferase and a nucleic acid encoding the sialyltransferase. The present invention also provides a microorganism producing the sialyltransferase, as well as a method for producing the sialyltransferase using such a microorganism. The present invention further provides a vector carrying a nucleic acid encoding the sialyltransferase, and a host cell transformed with the vector, as well as a method for producing a recombinant β-galactoside-α2,3-sialyltransferase. The present invention further provides a method for preparing a sialylsugar chain, which uses the sialyltransferase of the present invention.
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