Invention Grant
US08030045B2 Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
有权
β-丙氨酸/α-酮戊二酸氨基转移酶用于3-羟基丙酸生产
- Patent Title: Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
- Patent Title (中): β-丙氨酸/α-酮戊二酸氨基转移酶用于3-羟基丙酸生产
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Application No.: US12310503Application Date: 2007-08-17
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Publication No.: US08030045B2Publication Date: 2011-10-04
- Inventor: Holly Jean Jessen , Hans H. Liao , Steven John Gort , Olga V. Selifonova
- Applicant: Holly Jean Jessen , Hans H. Liao , Steven John Gort , Olga V. Selifonova
- Applicant Address: US MN Wayzata
- Assignee: Cargill, Incorporated
- Current Assignee: Cargill, Incorporated
- Current Assignee Address: US MN Wayzata
- International Application: PCT/US2007/076252 WO 20070817
- International Announcement: WO2008/027742 WO 20080306
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12N9/00 ; C12N1/20 ; C12N1/00 ; C12N15/00 ; C12P7/62 ; C12P7/52 ; C12P21/06 ; C12P19/34 ; C07H21/04
Abstract:
The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.
Public/Granted literature
- US20090291480A1 Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production Public/Granted day:2009-11-26
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