Invention Grant
US08030274B2 Method for treating asthma and chronic obstructive pulmonary disease (COPD) comprising administering FGF2
有权
治疗哮喘和慢性阻塞性肺疾病（COPD）的方法，包括给予FGF2
- Patent Title: Method for treating asthma and chronic obstructive pulmonary disease (COPD) comprising administering FGF2
- Patent Title (中): 治疗哮喘和慢性阻塞性肺疾病（COPD）的方法，包括给予FGF2
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Application No.: US11568896Application Date: 2005-05-12
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Publication No.: US08030274B2Publication Date: 2011-10-04
- Inventor: Yoon-Keum Kim , Soo Hyung Kang , Byong Moon Kim , Miwon Son
- Applicant: Yoon-Keum Kim , Soo Hyung Kang , Byong Moon Kim , Miwon Son
- Applicant Address: KR Seoul
- Assignee: Dong-A Pharmaceutical Co., Ltd.
- Current Assignee: Dong-A Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Lucas & Mercanti, LLP
- Priority: KR10-2004-0033261 20040512
- International Application: PCT/KR2005/001390 WO 20050512
- International Announcement: WO2005/107794 WO 20051117
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/50
Abstract:
The present invention relates an agent comprising FGF2 (Fibroblast Growth Factor-2 or basic Fibroblast Growth Factor (bFGF)) as an effective ingredient for treatment or prevention of Asthma and Chronic Obstructive Pulmonary Disease (COPD). Also, The present invention relates Th1 asthma and COPD mouse animal model induced by Ovalbumin and double strand RNA. The therapeutic agent comprising FGF2 of the present invention can be used for treatment or prevention for airway fibrosis, airway inflammation, airway hyperresponsiveness, airway remodeling, asthma and COPD. Also, Th1 asthma and COPD mice animal model induced by Ovalbumin and double strand RNA can be used for development of therapeutic agent for asthma and COPD.
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