Invention Grant
US08030284B2 Treatment of eye disorders characterized by an elevated intraocular pressure by siRNAs
有权
治疗以siRNA为特征的眼内压升高的眼部疾病
- Patent Title: Treatment of eye disorders characterized by an elevated intraocular pressure by siRNAs
- Patent Title (中): 治疗以siRNA为特征的眼内压升高的眼部疾病
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Application No.: US11574169Application Date: 2005-08-23
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Publication No.: US08030284B2Publication Date: 2011-10-04
- Inventor: Ana I. Jiménez , Ángela Sesto , José P. Roman , Irene Gascón , Gonzalo González de Buitrago
- Applicant: Ana I. Jiménez , Ángela Sesto , José P. Roman , Irene Gascón , Gonzalo González de Buitrago
- Applicant Address: ES Madrid
- Assignee: Sylentis S.A.U.
- Current Assignee: Sylentis S.A.U.
- Current Assignee Address: ES Madrid
- Agency: King & Spalding LLP
- Agent Kenneth H. Sonnenfeld; Margaret B. Brivanlou
- Priority: GB0418762.1 20040823; GB0503412.9 20050218
- International Application: PCT/GB2005/050134 WO 20050823
- International Announcement: WO2006/021817 WO 20060302
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/04
Abstract:
Sequences and protocols for treatment of eye conditions by use of RNA interference are disclosed. Target genes are selected from those responsible for aqueous flow or aqueous outflow, while particularly preferred conditions to be treated include glaucoma and uveitis.
Public/Granted literature
- US20070270365A1 Treatment of Eye Disorders Characterized by an Elevated Intraocular Pressure by siRNAs Public/Granted day:2007-11-22
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